Referring to the holdouts that refused to flee the coastal area, he said on Fox News: "Individuals who think they are tougher, stronger than Mother Nature -- God be with them."
Perry said some 1.2 million people had evacuated coastal Texas ahead of the storm.
Houston, the fourth largest US city with a metropolitan area population topping five million people, is just a few miles from the bay, and destruction there and along the coast in the hurricane zone is expected to be massive.
Jack Colley, from the Texas Department of Emergency Management, said officials estimated the storm's economic impact would be "somewhere in between the 80-billion dollar and 100-billion-dollar range."
"With Houston being home to some of the largest petrochemical complexes in the world, there's a tremendous amount of infrastructure there," Colley said.
Texas Senator Kay Bailey Hutchison also warned of the storm's economic consequences, saying "it's not just a regular rain and wind hurricane."
"The economic impact is going to be huge. People are much more concerned about this one than I have seen in a long long time," she said on Fox News. - AFP
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