Better cardiovascular health might guard against the damaging effects of these mutant genes - and perhaps prevent Alzheimer's, says John Hardy of University College London, a pioneer of the plaque hypothesis. "This is pushing very much on the idea that we should focus on heart fitness," he says.
Meanwhile, the third gene to be implicated in Alzheimer's was a variant of the PICALM gene, which draws fats and proteins into brain cells, and may also be active around synapses. The researchers suggest that the variant associated with Alzheimer's may cause too much fat to be drawn into cells, killing them.
What's more, in January research by Deborah Gustafson of the University of Gothenberg in Sweden linked obesity to a higher risk of Alzheimer's disease.
Nikos Scarmeas of Columbia University Medical Center in New York and colleagues found that the risk of Alzheimer's was reduced by a third in volunteers who were physically active, while those who ate a diet rich in fruit and vegetables lowered their risk by 40 per cent.
SHOOT: Shows you how ordinary health - eating properly and getting exercise - covers a multitude of sicknesses.
Meanwhile, the third gene to be implicated in Alzheimer's was a variant of the PICALM gene, which draws fats and proteins into brain cells, and may also be active around synapses. The researchers suggest that the variant associated with Alzheimer's may cause too much fat to be drawn into cells, killing them.
What's more, in January research by Deborah Gustafson of the University of Gothenberg in Sweden linked obesity to a higher risk of Alzheimer's disease.
Nikos Scarmeas of Columbia University Medical Center in New York and colleagues found that the risk of Alzheimer's was reduced by a third in volunteers who were physically active, while those who ate a diet rich in fruit and vegetables lowered their risk by 40 per cent.
SHOOT: Shows you how ordinary health - eating properly and getting exercise - covers a multitude of sicknesses.
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